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Vaccine and placebo clusters in the cluster randomized trial of OCV in Kolkata, India, 2006.

Journal: Frontiers in Public Health

Article Title: Assessing Vaccine Herd Protection by Killed Whole-Cell Oral Cholera Vaccines Using Different Study Designs

doi: 10.3389/fpubh.2019.00211

Figure Lengend Snippet: Vaccine and placebo clusters in the cluster randomized trial of OCV in Kolkata, India, 2006.

Article Snippet: Recently, we conducted a study using killed WC OCV as “vaccine probe” to determine geographic boundaries of person-to-person transmission of cholera in two different settings in which placebo-controlled, randomized trials of killed WC OCV had been conducted: Matlab, Bangladesh (which tested a killed cholera toxin B subunit (BS)-killed WC OCV and a killed WC-only OCV) and Kolkata, India (which tested a killed WC OCV) ( ).

Techniques: